[vc_row][vc_column][vc_column_text]Diabetic macular edema (DME) is a complication of diabetes that can cause vision problems and even blindness. It may be prevented or delayed with good diabetes management. Some medications are available to treat DME. Read on to learn more about diabetes and macular edema.[/vc_column_text][/vc_column][/vc_row][vc_row][vc_column][vc_column_text][ad-slot slotcode=’div-gpt-ad-lb-resp-cont1′][/vc_column_text][/vc_column][/vc_row][vc_row][vc_column][vc_column_text]
What is diabetic macular edema?
DME is an accumulation of excess liquid in the hollow spaces in the part of your eye called the macula. The macula is part of the retina and is located at the back of the eye. It is responsible for your central vision, which allows you to see shapes and colours clearly and sharply.
It is estimated that DME affects 7% of people living with diabetes.
Are diabetic macular edema and diabetic retinopathy the same?
DME and diabetic retinopathy are not the same condition, but they are related. Diabetic retinopathy is a disease that damages the blood vessels in the retina, resulting in impaired vision. When diabetic retinopathy is not treated quickly or effectively, fluid can leak into the macula, which results in DME.[/vc_column_text][read-also-article article-slug=”diabetic-eye-disease%c2%85/”][/vc_column][/vc_row][vc_row][vc_column][vc_column_text]
What causes diabetic macular edema?
The 3 most common causes of DME are:
What are the symptoms of diabetic macular edema?
Common symptoms of DME include:
- Blurred vision or double vision
- The presence of ‘floaters’ (small dark shapes that float across your vision); they can look like threads, squiggly lines, or little cobwebs
- Difficulty seeing colours
- Dark spots or blind spots in your field of vision
- Straight lines that you see as bent or curved
- Difficulty seeing when there is a glare or bright light
- Trouble reading
- Difficulty recognizing faces
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How is diabetic macular edema diagnosed?
If you are experiencing any of the symptoms noted above, it’s important to book an appointment with your diabetes healthcare team immediately. They will do a thorough eye examination and likely refer you to an eye specialist (ophthalmologist) for further tests.
The first test is an examination of your eye with a device called an ophthalmoscope. It allows your doctor to look at the back of your eye. This part of your eye is called the fundus, and consists of the retina, macula, optic disc and blood vessels.[/vc_column_text][vc_single_image image=”39647″ img_size=”full”][vc_column_text]If the ophthalmologist sees abnormalities during examination with an ophthalmoscope, they will likely order a test called optical coherence tomography. This test uses light waves to take cross-section pictures of your retina. The ophthalmologist can then review and analyze these pictures and determine if you have DME.
How is diabetic macular edema treated?
There is currently no cure for DME. However, optimal diabetes management and medications can help slow its progression and limit the amount of vision damage you may suffer.
When you have DME, your body makes too much of a protein called vascular endothelial growth factor (VEGF). This causes blood vessels to grow too quickly, so they’re weak and leak blood and fluid into your retina and macula. Anti-VEGF medications block the protein to help stabilize your blood vessels and prevent new ones from growing, which stops the leakage of fluid.
The anti-VEGF medicines used in Canada to treat DME are:
- Aflibercept (Eylea®)
- Bevacizumab (Avastin®)
- Ranibizumab (Lucentis®)
These medications are given by injection. You may be given an injection once a month for the first 3 to 6 months of treatment. After that, fewer injections are needed.
Another injectable medication was recently approved by Health Canada for people with DME. Faricimab (Vabysmo®) is a drug that targets both VEGF and angiopoietin-2, another protein that can build up in the eyes and contribute to DME. It is also administered by injection, but at less frequent intervals.
In addition to anti-VEGF medications, steroid injections, special eye drops that contain NSAIDs (non-steroidal anti-inflammatory drugs) and laser therapy are also used to treat DME.[/vc_column_text][/vc_column][/vc_row][vc_row][vc_column][vc_column_text][ad-slot slotcode=’div-gpt-ad-lb-resp-cont3′][/vc_column_text][/vc_column][/vc_row][vc_row][vc_column][vc_column_text]
Is there a way to prevent diabetic macular edema?
Like many other diabetes complications, the key to preventing DME is to manage your diabetes as effectively as possible. This means:
- Keeping your blood sugar at target levels
- Controlling your blood pressure and cholesterol levels
- Having an eye examination done regularly by an optometrist or ophthalmologist
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Are there any new treatments being developed to manage diabetic macular edema?
Some new and innovative treatments for DME are currently being studied, and include:
- High-dose anti-VGEF injections, which are given every 12 to 16 weeks instead of once a month
- Eye drops that deliver the medication directly to the affected eye
- Oral anti-VEGF medications, rather than injections
Good diabetes control can help prevent or delay eye complications such as DME. If you are at risk for DME, it’s important that you have your eyes tested regularly. If you develop DME, treatments are available that can help you manage the condition and slow its progression.[/vc_column_text][/vc_column][/vc_row]